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Browsing Науково-дослідний центр Інституту by Title

Now showing items 1-20 of 97

An interrelation of physical working capacity and body component composition indicators of amateur athletes

Gorenko Zoya; Ocheretko Boris; Kovelskaya Antonina; Горенко Зоя; Очеретько Борис; Ковельськая Антонина (Slobozhanskyi herald of science and sport, 2017)

Purpose: determine the features of the body component composition and the level of physical performance, as well as the structure of the correlation between these indicators in amateur athletes. Material & Methods: in ...
Association between hypoxia level in gastric cancer, assessed by 31P NMR spectroscopy, and results of patients treatment with different methods

Осинський Д. С.; Бубновська Л. М.; Ковельська А. В.; Меренцев С. (Онкология, 2014)

Aim: to analyse the association between gastric cancer hypoxia level and results of patients treatment. Patients and methods: the specimens of primary gastric cancer were investigated. 150 naïve patients were enrolled ...
Bioenergetic status and hypoxia in Lewis lung carcinoma assassed by 31P NMR spectroscopy: correlation with tumor progression.

Bubnovskaya L.; Mikhailenko V.; Kovelskaya A.; Osinsky S. (Experimental Оncology, 2007)

Aim: Тo evaluate the hypoxia level and some indices of Lewis lung carcinoma energy metabolism by means of 31Р NMR spectroscopy in perchloric acid (PCA) tissue extracts during growth of primary tumor and metastasis. Мaterials ...
CD8 and CD45RO T lymphocytes in bone marrow of gastric cancer patients: correlation with disseminated tumor cells and disease outcome

Osinsky S.; Kovelskaya A.; Bubnovskaya L.; Osinsky D.; Merentsev S. (Experimental Оncology, 2015)

Aim: To evaluate the association between the presence of CD8 and CD45RO T lymphocytes in bone marrow (BM), disseminated tumor cells (DTCs), tumor hypoxia and their impact on disease outcome. Material and methods: 91 naïve ...
CD8 та CD45RO T лімфоцити у кістковому мозку хворих на рак шлунка та перебіг мінімальної залишкової хвороби

Ковельська А. В.; Бубновська Л. М.; Осинський С. П.; Осинський Д. С. (Онкология, 2015)

Вступ. Проблема мінімальної залишкової хвороби (МЗХ) при солідних пухлинах нині є однією з центральних у дослідженнях експериментальної та особливо клінічної онкології. Доведено, що дисеміновані пухлинні клітини (ДПК) на ...
CXCR4 Expression in Gastric Cancer and Bone Marrow: Association with Hypoxia-Regulated Indices, Disseminated Tumor Cells, and Patients Survival.

Osinsky, D; Kovelskaya, A; Bubnovskaya, L; Ganusevich, I; Gumenyuk, L; Merentsev, S; Osinsky, S; Mamontova, L (Journal of Cancer Research, 2015)

Aim:The analysis of the association of CXCR4 expression in gastric cancer (GC) and bone marrow (BM) with clinical characteristics. Patients and Methods: 65 patients with GC were investigated. Immunohistochemistry, ...
Detection of tumor response to Co(III) and Fe(III) complexes by 31P-Nuclear Magnetic Resonance Spectroscopy

Bubnovskaya L.; Mikhailenko V.; Kondrichin I.; Osinsky S.; Kovelskaya A.; Sigan A.; Levitin I. (Экспериментальная онкология, 2002)

A comparative analysis of the effects of several Co (III) and one Fe (III) complexes, as well as that of CoCl2 on the “bioenergetic status” as well as tumor hypoxia in Guerin carcinoma has been carried out using 31P NMR. ...
Disseminated tumor cells in bone marrow of gastric cancer patients: correlation with tumor hypoxia and clinical relevance

Kovelskaya A.; Bubnovskaya L.; Gumenyuk L.; Mamontova L.; Mikhailenko V.; Osinsky D.; Merentsev S.; Osinsky S. (Journal of Oncology, 2014)

The evaluation of the clinical relevance of disseminated tumor cells (DTCs) in bone marrow (BM) of patients with gastric cancer (GC) and their association with primary tumor hypoxia. Patients and Methods. 89 resected ...
Expression of CXCR4 in tumor and bone marrow of gastric cancer patients: association with hypoxia-regulated indices, disseminated tumor cells and survival

Osinsky D.; Kovelskaya A.; Bubnovskaya L; Ganusevich I.; Gumenyuk L.; Merentsev S.; Osinsky S.; Mamontova L. (Annals of Oncology, 2014)

Aim: CXCR4 expression is associated with metastasis and poor outcome of various cancers but its role in gastric cancer (GC) is still unclear. This study was aimed to analyze the association of CXCR4 expression in GC and ...
Functional dichotomy (symmetry – asymmetry) of physical development in men who are engaged in triathlon

Gorenko Zoya; Ocheretko Boris; Kovelskaya Antonina; Горенко Зоя; Очеретько Борис; Ковельськая Антонина (Slobozhanskyi herald of science and sport, 2018)

Purpose: explore the dichotomy of the physical development of men who are engaged in triathlon and long-distance running on the highway. Conclusion: most amateur athletes who practice triathlon or long-distance runner on ...
Hypoxia level and matrix metalloproteinases-2 and -9 activity in Lewis lung carcinoma: correlation with metastasis

Osinsky S.; Ganusevich I.; Bubnovskaya L.; Valkovskaya N.; Kovelskaya A.; Sergienko T.; Zimina S. (Experimental Оncology, 2005)

To investigate the relationship between tumor hypoxia in vivo, activiti of matrix metalloproteinases (MMPs), and metastatic potential of tumor.
Hypoxia, tumour-associated macrophages, microvessel density, VEGF and matrix metalloproteinases in human gastric cancer: interaction and impact on survival.

Kovelskaya A. (Ковельська А.); Bubnovskaya L. (Бубновська Л.); Ganusevich I. (Ганушевич І.); Osinsky S. (Осінський С.); Gumenyuk L. (Гуменюк Л.); Merentsev S. (Меренцев С.); Olijnichenko G. (Clinical Translational Oncology, 2011)

Introduction: Hypoxia is a key feature of the microenvironment of cancer cells actively participating in tumour progression. Our study was aimed to evaluate the impact of hypoxia and hypoxia-associated factors on tumour ...
Hypoxia-regulated proteins (HRPs) and matrix metalloproteinases (MMPs) in gastric cancer: impact on malignant progression

Osinsky S.; Bubnovskaya L.; Ganusevich I.; Kovelskaya A.; Yurchenko O.; Gumenyuk L.; Chorny A. (Clinical and Translational Oncology, 2004)

To evaluate the interrelationship between hypoxia level, expression of HRPs and activity of MMPs in tumor tissue and assess the impact of these parameters on malignant progression.
Influence of psychoemotional stress on the functional state of the neuromuscular system and the efficiency of sensorimotor activity of highly skilled athletes

Fedorchuk Svitlana; Lysenko Olena; Kolosova Olena; Khalyavka Tetiana; Romaniuk Volodymyr (SlobozhanSkyi herald of Science and Sport, 2017)

Purpose: assessment of the influence of the level of psychoemotional stress and the effectiveness of mental self-regulation on the functional state of the neuromuscular system and the effectiveness of the sensorimotor ...
Interrelation between the level of stress and the functional state of the neuromuscular system of athletes-tennisists

Lysenko, O.; Fedorchuk, S.; Kolosova, O.; Khalyavka, T. (Здоров’я, фізичне виховання і спорт: перспективи та кращі практики: матеріали Міжнар. наук.-практ. конф., 15 травня 2018 р., Київ, 2018)
Nanohyperthermia of malignant tumors. I. Lanthanum-strontium manganite magnetic fluid as potential inducer of tumor hyperthermia

Solopan S.; Belous A.; Yelenich A.; Kovelskaya A.; Chekhun V.; Podoltsev A.; Kondratenko I.; Osinsky S. (Experimental Оncology, 2011)

To synthesize magnetic particles of lanthanum-strontium manganite, prepare the magnetic fluid (MF), evaluate the generation of heat by particles and determine their common toxiсity. Methods: Nanoparticles based on the solid ...
Nanohyperthermia of malignant tumors. II. In vivo tumor heating with manganese perovskite nanoparticles.

Kovelskaya A.; Bubnovskaya L.; Belous A.; Solopan A.; Podoltsev A.; Kondratenko I.; Sergienko T.; Osinsky S. (Экспериментальная онкология, 2012)

To evaluate the ability of manganese perovskite nanoparticles (lanthanum-strontium manganite) to heat the tumor tissue in vivo under action of external alternating magnetic field. Materials and Methods: The magnetic fluid ...
Redox-active cobalt complexes as selective anticancer agents: mechanisms of activity

Osinsky S.; Bubnovskaya L.; Levitin I.; Sigan A.; Ganusevich I.; Kovelskaya A.; Valkovskaya N.; Campanella L.; Wardman P. (British Journal of Cancer, 2003)

To study mechanisms of biological activity of novel cobaltcomplexes (CoC) displaing anticancer effect.
Relationship of indicators of oxygen-containing blood elements with the duration of systematic triathlon training for amateur athletes

Kovelskaya Antonina; Gorenko Zoya; Ocheretko Boris; Ковельськая Антонина; Горенко Зоя; Очеретько Борис (Slobozhanskyi herald of science and sport, 2018)

Purpose: to investigate the nature of changes in the indicators of oxygen-containing blood elements in amateur athletes with different duration of systematic triathlon training. Material & Methods: peripheral blood taken ...
Selectivity of effects of redox-active cobalt (III) complexes on tumor tissue

Osinsky S.; Levitin I.; Sigan A.; Bubnovskaya L.; Ganusevich I.; Kovelskaya A.; Valkovskaya N.; Campanella L.; Wardman P. (Experimental Оncology, 2004)

Aim: To estimate the selectivity of action of cobalt complexes on tumor tissue. Materials and Methods: Cobalt (III) complexes containing both the tetradentate Schiff-base ligand derived from acetylacetone and ethylenediamine, ...

Now showing items 1-20 of 97

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