Перегляд Науково-дослідний центр Інституту по темі "Hypoxia tumor"

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CD8 and CD45RO T lymphocytes in bone marrow of gastric cancer patients: correlation with disseminated tumor cells and disease outcome

Osinsky S.; Kovelskaya A.; Bubnovskaya L.; Osinsky D.; Merentsev S. (Experimental Оncology, 2015)

Aim: To evaluate the association between the presence of CD8 and CD45RO T lymphocytes in bone marrow (BM), disseminated tumor cells (DTCs), tumor hypoxia and their impact on disease outcome. Material and methods: 91 naïve ...
CXCR4 Expression in Gastric Cancer and Bone Marrow: Association with Hypoxia-Regulated Indices, Disseminated Tumor Cells, and Patients Survival.

Osinsky, D; Kovelskaya, A; Bubnovskaya, L; Ganusevich, I; Gumenyuk, L; Merentsev, S; Osinsky, S; Mamontova, L (Journal of Cancer Research, 2015)

Aim:The analysis of the association of CXCR4 expression in gastric cancer (GC) and bone marrow (BM) with clinical characteristics. Patients and Methods: 65 patients with GC were investigated. Immunohistochemistry, ...
Hypoxia-regulated proteins (HRPs) and matrix metalloproteinases (MMPs) in gastric cancer: impact on malignant progression

Osinsky S.; Bubnovskaya L.; Ganusevich I.; Kovelskaya A.; Yurchenko O.; Gumenyuk L.; Chorny A. (Clinical and Translational Oncology, 2004)

To evaluate the interrelationship between hypoxia level, expression of HRPs and activity of MMPs in tumor tissue and assess the impact of these parameters on malignant progression.

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