Перегляд Науково-дослідний центр Інституту по Автору "Gumenyuk L."

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Disseminated tumor cells in bone marrow of gastric cancer patients: correlation with tumor hypoxia and clinical relevance

Kovelskaya A.; Bubnovskaya L.; Gumenyuk L.; Mamontova L.; Mikhailenko V.; Osinsky D.; Merentsev S.; Osinsky S. (Journal of Oncology, 2014)

The evaluation of the clinical relevance of disseminated tumor cells (DTCs) in bone marrow (BM) of patients with gastric cancer (GC) and their association with primary tumor hypoxia. Patients and Methods. 89 resected ...
Expression of CXCR4 in tumor and bone marrow of gastric cancer patients: association with hypoxia-regulated indices, disseminated tumor cells and survival

Osinsky D.; Kovelskaya A.; Bubnovskaya L; Ganusevich I.; Gumenyuk L.; Merentsev S.; Osinsky S.; Mamontova L. (Annals of Oncology, 2014)

Aim: CXCR4 expression is associated with metastasis and poor outcome of various cancers but its role in gastric cancer (GC) is still unclear. This study was aimed to analyze the association of CXCR4 expression in GC and ...
Hypoxia-regulated proteins (HRPs) and matrix metalloproteinases (MMPs) in gastric cancer: impact on malignant progression

Osinsky S.; Bubnovskaya L.; Ganusevich I.; Kovelskaya A.; Yurchenko O.; Gumenyuk L.; Chorny A. (Clinical and Translational Oncology, 2004)

To evaluate the interrelationship between hypoxia level, expression of HRPs and activity of MMPs in tumor tissue and assess the impact of these parameters on malignant progression.

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